Recent Invitations

DGMB invites you to submit matrix-centric or lab-related images for potential display on the DGMB website banner!

Would you like to showcase your research? Are you proud of your histology, immunostaining, (F)ISH, EM data? Do you have some captivating images related to your recent publication that you didn’t include in the manuscript? Perhaps you’d even like to share images that capture the essence of your daily lab routine?

Submission deadline is October 31st, 2023


In memory of

Prof. Dr. Dr. h.c. Klaus Kühn

*1.5.1927     † 7.4.2022


Klaus Kühn was a pioneer in collagen research with landmark discoveries in the collagen field, who shaped a sustainable extracellular matrix research in Germany and throughout the world. The passionate collagen scientist was fascinated by the collagen tripelhelix and was always a leading, highly motivating figure in the field who encouraged generations of young people to climb apparently unsurmountable summits.

Somehow, it happened that every chair in matrix biology research in Germany came from or went through Klaus Kühn‘s lab. The German Society for Matrix Biology and the worldwide matrix biology community is greatly saddened by the passing of Klaus Kühn.


Klaus Kühn had managed to establish an extremely successful international research center while maintaining a kind and collegial atmosphere within the department, welcoming students and scientists from all over the world. This was unique in the highly hierarchical academic structure in Germany at that time. Klaus Kühn was proud to be a typical chemist but he welcomed initiatives to approach connective tissue research from many different angles and he was always very interested in medical issues. He enjoyed scientific discussions as well as playing tennis with the members of his department. There is no doubt that he had a profound influence on our scientific, academic and personal life.

Monique Aumailley and Thomas Krieg

Er hinterlässt uns allen das Bild einer eindrücklichen, großzügigen, immer bescheidenen und liebenswürdigen Forscherpersönlichkeit. Sein Lebenswerk umfasst eine große Zahl von Wissenschaftlern, deren Entwicklung und Karriere er nachhaltig beeinflusst hat, eine zusätzliche Leistung, die alles andere als eine Selbstverständlichkeit ist. Wir alle sind ihm dafür zu Dank verpflichtet.

Peter Bruckner

Er war ein ausgezeichneter Lehrmeister, der wissenschaftliche Expertise mit einer fürsorglichen Menschlichkeit verband. Unvergesslich ist, wie er junge Wissenschaftler in die Wissenschaftsgemeinde der Extrazellulären Matrix integrierte. Der offene Wissenschaftsaustausch und die angenehme Umgebung auf Matrix-Tagungen ist auch sein Verdienst. Für sein prägendes Vorbild, Wissenschaft menschlich zu machen, bin ich ihm sehr dankbar. Ich bewahre ihn in Erinnerung.

Johannes Eble

Klaus Kühn was a pioneer, a titan of collagen research, and an excellent teacher and mentor. His scientific heritage and mentorship left lasting marks on connective tissue research, both in- and outside Germany. Even after his retirement, Klaus Kühn often visited his beloved Max Planck Institute of Biochemistry and always stopped by in my department to talk about the latest breakthroughs in matrix and adhesion research. His visits, discussions, support and advice will always remain in my memory.

Reinhard Fässler

Nicht nur die Wissenschaft, sondern auch viele muntere und warmherzige Treffen hat mich mit Klaus Kühn verbunden. Es sind nicht zuletzt diese Runden in anspruchsvoller Konversation und freundschaftlich, verbindlicher Atmosphäre, die uns in Erinnerung bleiben und die uns deutlich machen, welch menschlicher Verlust der fast gemeinsame Tod von Barbara und Klaus für uns bedeutet.

Verena Gauss-Müller & Peter Müller

I first got to know Klaus Kühn in 1983 when I joined Rupert Timpl´s group in the Kühn department in Martinsried. Later there were many more meetings, in particular at the famous retreats at Schloss Ringberg. Klaus was an outstanding scientist, but also a very kind and supportive mentor. I much appreciated the generosity with which he led his department. He gave us great freedom and a main priority was always the development of his younger coworkers. For this reason many of us stayed as long as ever possible. He became my role model with regard to scientific leadership. I feel deep sorrow.

Mats Paulsson

Klaus Kühn war für uns immer ein Fixpunkt als brillanter, stimulierender und immer neugieriger Wissenschaftler. Es war ein Erlebnis in seiner Abteilung, auch wenn er es einem nicht immer ganz leicht machte. Ein besonderer Mensch der Güte und Menschlichkeit ausstrahlte und dabei versuchte, die nächste Generation zu fordern und das Beste in ihnen zu fördern. In diesem Sinne erfüllt uns der Verlust mit Trauer aber auch menschlicher Dankbarkeit.

Ernst Pöschl & Ulrike Mayer

Ich werde Klaus Kühn als Freund, verständnisvollen Doktorvater, effizienten Institutsleiter und großen Wissenschaftler in Erinnerung behalten, der nicht nur die Wissenschaftsszene in Deutschland entscheidend geprägt hat, sondern auch den nachfolgenden Generationen die Erkenntnis mitgegeben hat, zu welcher Tiefe, Freude und Erfolg koordinierte Forschung im Team führen kann.

Klaus von der Mark

If you also wish to submit a personal obituary contact us.

Open Job Positions

Here you can find open job positions from our members and partners. If you also want to see your job offer here just write us a quick message via the contact form.

Postdoc position in immuno-oncology available immediately for 24 months in the OREND -Tumor Microenvironment Laboratory, Strasbourg, France.

The appointed postdoc will use state of the art technology in immunology and matrix research and will work within a consortium of colleagues experienced in matrix biology, immunology, omics and network analysis in frame of the INCa funded TENMAX project. Aims of this project are to (1) understand and (2) target the tumor immuno-landscape for developing novel anti-cancer targeting strategies.

The position is located at the Institut d’Hématologie et d’Immunologie in the center of Strasbourg (France) and is available for 24 months, starting in June 2023. INSERM U1109 ( is associated with the University of Strasbourg and with the Doctoral School of Life Sciences and Health.

We are looking for a highly motivated candidate with a recent PhD in tumor immunology or related fields and an excellent academic record. The candidate must have a strong background in tumor molecular biology and experience in murine tumor models, histology, cell culture, biochemistry and flow cytometry. Specific expertise in bioinformatics is a plus. The candidate should be able to think independently and creatively, and have excellent written and oral communication skills in English. The candidate shall work well in the team, supervise Master and PhD students, and present the project and results to scientists and the public. She/he will participate in extensive collaborations with the 5 partner laboratories involved in the project.

Please send a motivation letter expressing your interest and suitability for the project, CV and publication list, and the names and e-mail addresses of two references. For further details and information see, and contact Gertraud Orend:

Postdoc position (TV-L E13) available immediately for 2-3 years in the research group “Translational Matrix Biology“ at University of Cologne, Medical Faculty, Germany.

This position is funded within a DFG research grant focusing on mechanisms controlling collagen secretion. The aim of this project is to understand and modulate collagen secretion, ultimately aiming at developing novel therapeutic approaches to target fibrotic diseases. We are looking for a highly motivated candidate with a solid background in molecular & cell biology and/or protein chemistry. Hands-on experience in animal experimentation (FELASA-B) is desired.

We are a small international team of scientists embedded in the vibrant Cologne life science environment with basic science and translational groups (CECAD, CMMC, University hospital, MPI Age, MPI Metabolism) closely collaborating.

Interested candidates are invited to send their CV and contacts of 2 references to:

Prof. Dr. Thomas Krieg

Download the flyer.

Open PhD Student Position (65 %, E13) in the Division for Biochemistry of Joint and Connective Tissue Diseases, Orthopedic Department, University Hospital of Ulm

Project: Elucidating the pathomechanisms of compromised fracture healing in osteoporosis: Consequences of mitochondrial dysfunction

Osteoporosis is a major health problem characterized by compromised bone strength and consequent increased risk of fracture and impaired healing capacities. So far, the underlying pathomechanisms are only poorly understood and pharmacologic approaches are limited. Our project aims on further investigation of the molecular pathomechanisms of osteoporosis, in particular cellular aging and mitochondrial dysfunction, and testing of novel therapeutics strategies to improve bone healing after fracture. The project is part of the Collaborative Research Centre 1149 (CRC1149) “Danger response, disturbance factors and regeneration after acute trauma” and will be performed in the group of Dr. Jana Riegger-Koch at the RKU (
Activities and responsibilities:
• human/ mouse primary cell culture, differentiation of mesenchymal stem cells
• molecular biological techniques: gene expression analysis, ELISA, WB, …
• histology: fluorescence staining, immunohistochemistry (IHC)
• writing publications and presentation of own results on conferences/ retreats
Qualification profile:
• master degree in biology, molecular medicine or related field of study
• strong motivation to address bio-medical and pathophysiological questions
• experience in cell and molecular biology, and possibly first insight into animal experiments would be an advantage
We offer:
• direct supervision and training in established methods
• close cooperation with other CRC1149 members
• opportunity to join the International Graduate School in Mol. Medicine Ulm
• development your own scientific profile, incl. additional training opportunities
• funding for 4 years (65 %, E13); starting in February 2023
Detailed applications (CV, certificates etc.) should be send until 8th of January to Dr. Jana Riegger-Koch via mail: For further information download the flyer. Please feel free to contact Dr. Riegger-Koch for further information or visit our homepage

PhD student positions in the German Research Foundation (DFG) funded Research Unit FOR2722 “ECM biology and musculoskeletal diseases” 

The Research Unit has an open call for 17 PhD student positions to join our network of excellent and passionate scientists located in one of the most vibrant cities in the center of Europe – Cologne. We work on the extracellular matrix (ECM), the complex and highly information-containing molecular network that surrounds cells. The ECM influences most aspects of cellular function by binding to cell surface receptors or modulating growth factor signalling. It is thereby intimately  involved in many forms of inherited or acquired disease.
Join our vivid network on extracellular matrix biology & musculoskeletal diseases and make a difference!
– Work with leading experts on connective tissue diseases, uncover novel molecular pathomechanisms and develop tailored therapies.
– Enjoy a highly interdisciplinary research environment with 18 internationally recognized group leaders from basic science to translational medicine with focus on mechanobiology, systems biology, biochemistry, molecular and developmental biology, human genetics and diseases, clinical translation.
– Interact with groups of our collaborative research network at renowned institutions: The Childrens Hospital & research institutes of the University of Cologne – the German Sport University Cologne – the Max Planck Institute for the Biology of Aging – the Cluster of Excellence CECAD – the Institute for Musculoskeletal Medicine (Münster) – the Dr. Rolf M. Schwiete Research Unit (Frankfurt)

You will benefit from
– Excellent projects that address basic and translational questions in extracellular matrix biology and connective tissue diseases
– Access to advanced imaging/mass spectrometry/genomic & gene editing technologies, disease models (mouse, fish, organoids) and translational approaches (protein targeting & therapeutic antibody development)
– Advanced training, mentoring and networking in a cohort of PhD students entirely dedicated to the extracellular matrix and connective tissue diseases
– Training workshops in extracellular matrix biology and musculoskeletal diseases, high throughput data analysis and clinical aspects of connective tissue diseases
– Soft skills courses (presentation & scientific writing, good scientific conduct)
– Structured PhD programme and thesis advisory committees
– Participation and organization of summer schools, seminar series, annual retreats and international symposia
– Mobility grants for national and international short term lab visits
– Full funding for international and German students, no tuition costs

We invite
highly motivated applicants with an MSc (or equivalent) degree and a strong background in life sciences e.g. biochemistry, molecular medicine, pharmacy, veterinary medicine, medicine and bioengineering.

Apply now and send your application including a letter of motivation, copy of certificates, a CV and names of two references to
For further information download the flyer, visit us on Twitter @DFG_FOR2722 or

Doctoral researcher (PhD student) position in the area of rare skeletal diseases

In the research group “Skeletal Pathobiochemistry” at the University Medical Center Hamburg-Eppendorf (UKE) we are interested in the molecular basis of rare genetic diseases affecting bone and cartilage tissues in the early years of life. Our newly funded project aims to explore the molecular pathomechanisms of an ultra-rare, X-linked form of osteogenesis imperfecta. The position is to be filled with 65% (TVöD/VKA E13) of the regular weekly working hours and is to be occupied at the earliest possible date. The position is funded by the German Research Foundation (DFG) for a period of three years.

Contact: Dr. Tatyana Danyukova, Tel.: (040)7410-58780, E-mail:

Application should include full CV, academic transcript(s) and/or certificates, a brief statement of your research interests and contact information of 2-3 references. Please send your application as a single PDF file to by 20th January 2023 (reference code WS22901).

For more information about our research group, please visit us here visit us here

For more information about the position and how to apply, please visit the UKE career web-page

Post Doctoral Researcher in Lyon

The research group of Catherine Moali in the LBTI (Tissue Biology and Therapeutic Engineering Lab, Lyon, France, ) is looking for a Post Doctoral Researcher (for minimum of 2 years) to work on the  structure-function analysis of the proteolytic maturation complex of fibrillar collagens. Our keywords : extracellular matrix, collagen, proteases, mechanism, structure, CryoEM.  The project aims to better understand the steps leading from the synthesis of individual procollagen chains to collagen fibrils and would greatly benefit the development of new therapeutic tools targeting fibrotic diseases. Project in collaboration with the OPIC (Oxford Particle Imaging Center) facility in Oxford.

LBTI is a young and dynamic research laboratory located in the heart of Lyon Biodistrict (>5000 people working in life sciences and biomedical research). It offers top-level equipment in biology and a very stimulating scientific environment. Located in the South-East of France, Lyon is the second biggest scientific and economic center in the country and is internationally recognized for its quality of life.

Find out more and apply and download the flyer


Two junior faculty positions in the area of tissue biology to be based at the Kennedy Institute of Rheumatology, University of Oxford

Following a recent strategic review, tissue biology has been identified as high priority for the Institute and an area for investment from the Kennedy Trust for Rheumatology Research (KTRR). Accordingly, in 2022, in combination with funding from KTRR and Versus Arthritis, we launched a new Tissue Biology Platform, led by Professor Tonia Vincent.

The new faculty members will play a vital role in developing the Tissue Biology Platform by bringing expertise in areas such as the extracellular matrix, tissue niche, stem cell biology, in vitro human organoids and proteomics. Tissues of interest might include, but are not restricted to, bone, cartilage, synovium, endothelium and epithelium. There is a strong translational ethos at the Institute with an emphasis on inflammatory, mechano-inflammatory and fibrotic diseases.

The two positions are distinct, with a senior position “Group Leader in Tissue Biology” most suited to an established scientist wishing to pursue a pure academic track, and “Group Leader (Innovation Investigator Track) in Tissue Biology” which would suit a more junior person where there would be an expectation that 50% of their time was used to help support collaborative activities across the Institute (this could include technology-based expertise).

Links to the two job descriptions with details on how to apply: Group Leader in Tissue Biology and Group Leader (Innovation Investigator Track) in Tissue Biology

We also have funding for a post doc in proteomics to support mass spec analysis across the Institute. This post would suit a recent PhD graduate, or more established PDRA, with hands on experience in proteomic and/or lipidomic analysis.

12 Doctoral Candidate positions – MSCA – “Cellular Homeostasis ANd AGing in Connective TissuE Disorders” (CHANGE) in the framework of the Horizon Europe Marie Curie Doctoral Network

CHANGE is a Marie Sklodowska-Curie Doctoral Network (MSCA-DN) focused on investigating connective tissue (CT) disorders to identify key players in age-related decline in physiological functions to develop therapeutic strategies and identify treatment targets for common diseases and frailty associated with aging. It is part of Horizon EUROPE programme of the European Union and 12 Doctoral Candidates (DC) will be appointed for 36 months each.

CHANGE project – summary

Lifespan has significantly increased but age-related disorders severely limit healthy aging and quality of life, and are a serious burden for the society. Musculoskeletal, cardio- and cerebrovascular failure are hallmarks of physical and cognitive decline in the elderly, but importantly, are also common traits in several early onset hereditary connective tissue disorders.

In CHANGE, 12 young scientists will combine skills in musculoskeletal and vascular developmental and cellular biology and pathobiology related to aging, with expertise in cell culture, animal models, -omics, innovative high-resolution imaging and functional techniques. Exchange of knowledge and multidisciplinary collaboration between these fields of research and partners within the consortium will provide the skills, multidisciplinary knowledge and on-the-job training experience necessary to tackle the main aspects of biology of aging and age-related disorders affecting bone, cartilage, muscle and vasculature.

PhD positions

The consortium consists of partners from academia and industry with excellent scientific qualifications in multiple disciplines. In total, there are 12 open PhD positions for DCs within CHANGE. Each DC will be appointed at one of the consortium partners but secondments and regular meetings will be performed at other partners to ensure multidisciplinary training and close collaboration. An ideal DC candidate will hold a Master’s degree with excellent marks from her/his previous studies and experience in one or more of the relevant broad research fields will be an advantage. Excellent written and oral communication skills in English are essential. The DCs will start their projects between September 2022 and March 2023.

More details here.

To apply for this position, send your CV, motivation letter and at least a reference letter to the following email address:

Please state the DC reference (CHANGE DC number) in the subject line. If you would like to apply for more than one position, please indicate your first and second preference.

Short listed Applicants will be interview by the Trainee Committee.



Sigle M, Rohlfing AK, Kenny M, Scheuermann S, Sun N, Graeßner U, Haug V, Sudmann J, Seitz CM, Heinzmann D, Schenke-Layland K, Maguire PB, Walch A, Marzi J, Gawaz MP.
Translating genomic tools to Raman spectroscopy analysis enables high-dimensional tissue characterization on molecular resolution.
19 Sep 2023,

Prag HA, Murphy MP, Krieg T.
Sox-2 positive cells identified in lymph nodes from endometriosis patients may play a role in the disease pathogenesis.
1 Sep 2023,

Anderle N, Schäfer-Ruoff F, Staebler A, Kersten N, Koch A, Önder C, Keller AL, Liebscher S, Hartkopf A, Hahn M, Templin M, Brucker SY, Schenke-Layland K, Schmees C.
Breast cancer patient-derived microtumors resemble tumor heterogeneity and enable protein-based stratification and functional validation of individualized drug treatment.
18 Aug 2023,

Rösch G, Zaucke F, Jenei-Lanzl Z.
Autonomic nervous regulation of cellular processes during subchondral bone remodeling in osteoarthritis.
1 Aug 2023,

Ewald CY, Nyström A.
Mechanotransduction through hemidesmosomes during aging and longevity.
1 Aug 2023,

Hsu CP, Aretz J, Hordeichyk A, Fässler R, Bausch AR.
Surface-induced phase separation of reconstituted nascent integrin clusters on lipid membranes.
1 Aug 2023,

Luik AL, Hannocks MJ, Loismann S, Kapupara K, Cerina M, van der Stoel M, Tsytsyura Y, Glyvuk N, Nordenvall C, Klingauf J, Huveneers S, Meuth S, Jakobsson L, Sorokin L.
Endothelial basement membrane laminins - new players in mouse and human myoendothelial junctions and shear stress communication.
1 Aug 2023,

Brenneis M, Junker M, Sohn R, Braun S, Ehnert M, Zaucke F, Jenei-Lanzl Z, Meurer A.
Patellar malalignment correlates with increased pain and increased synovial stress hormone levels-A cross-sectional study.
27 Jul 2023,

Injarabian L, Willenborg S, Welcker D, Sanin DE, Pasparakis M, Kashkar H, Eming SA.
FADD- and RIPK3-Mediated Cell Death Ensures Clearance of Ly6Chigh Wound Macrophages from Damaged Tissue.
27 Jul 2023,

Sawant M, Wang F, Koester J, Niehoff A, Nava MM, Lundgren-Akerlund E, Gullberg D, Leitinger B, Wickström S, Eckes B, Krieg T.
Ablation of integrin-mediated cell-collagen communication alleviates fibrosis.
21 Jul 2023,

Burmeister M, Fraunenstein A, Kahms M, Arends L, Gerwien H, Deshpande T, Kuhlmann T, Gross CC, Naik VN, Wiendl H, Klingauf J, Meissner F, Sorokin L.
Secretomics reveals gelatinase substrates at the blood-brain barrier that are implicated in astroglial barrier function.
21 Jul 2023,

Lau C, Muthu ML, Siddiqui IF, Li L, Reinhardt DP.
High fat diet has a protective sex-dependent effect on aortic aneurysm severity in a Marfan syndrome mouse model.
21 Jul 2023,

Rafaeva M, Jensen ARD, Horton ER, Zornhagen KW, Strøbech JE, Fleischhauer L, Mayorca-Guiliani AE, Nielsen SR, Grønseth DS, Kuś F, Schoof EM, Arnes L, Koch M, Clausen-Schaumann H, Izzi V, Reuten R, Erler JT.
Fibroblast-derived matrix models desmoplastic properties and forms a prognostic signature in cancer progression.
18 Jul 2023,

Paul Konken C, Beutel B, Schinor B, Song J, Gerwien H, Korpos E, Burmeister M, Riemann B, Schäfers M, Sorokin L, Haufe G.
Influence of N-arylsulfonamido d-valine N-substituents on the selectivity and potency of matrix metalloproteinase inhibitors.
15 Jul 2023,

Kaps J, Georgieva VS, Oberholz L, Kribs A, Brachvogel B, Keller T.
Human preterm colostrum stimulates outgrowth in neurogenic tissue.
11 Jul 2023,

Etich J, Semler O, Stevenson NL, Stephan A, Besio R, Garibaldi N, Reintjes N, Dafinger C, Liebau MC, Baumann U, Mörgelin M, Forlino A, Stephens DJ, Netzer C, Zaucke F, Rehberg M.
TAPT1-at the crossroads of extracellular matrix and signaling in Osteogenesis imperfecta.
10 Jul 2023,

Li S, Kong Z, Ma B, Wang H, Han Y, Zhao H, Shi X, Lv P, Yue H, Grässel S, Yin L.
Low miR-182-5p Expressing Extracellular Vesicles Derived From Human Bone Marrow Stromal Cells of Subjects With Steroid-Induced Osteonecrosis of the Femoral Head Aggravate Disease Progression.
1 Jul 2023,

Becker L, Montes-Mojarro IA, Layland SL, Nsair A, Fend F, Marzi J, Schenke-Layland K.
Exploring the relationship between epigenetic DNA methylation and cardiac fibrosis through Raman microspectroscopy.
1 Jul 2023,

Zhu M, Metzen F, Hopkinson M, Betz J, Heilig J, Sodhi J, Imhof T, Niehoff A, Birk DE, Izu Y, Krüger M, Pitsillides AA, Altmüller J, van Osch GJVM, Straub V, Schreiber G, Paulsson M, Koch M, Brachvogel B.
Ablation of collagen XII disturbs joint extracellular matrix organization and causes patellar subluxation.
28 Jun 2023,

Gude F, Froese J, Steffes G, Grobe K.
The role of glycosaminoglycan modification in Hedgehog regulated tissue morphogenesis.
28 Jun 2023,

Bodescu MA, Aretz J, Grison M, Rief M, Fässler R.
Kindlin stabilizes the talin·integrin bond under mechanical load by generating an ideal bond.
27 Jun 2023,

Hammersen T, Buchert J, Zietzschmann S, Diederichs S, Richter W.
Inverse Regulation of Cartilage Neogenesis at Physiologically Relevant Calcium Conditions by Human Articular Chondrocytes and Mesenchymal Stromal Cells.
18 Jun 2023,

Lu CE, Levey RE, Ghersi G, Schueller N, Liebscher S, Layland SL, Schenke-Layland K, Duffy GP, Marzi J.
Monitoring the macrophage response towards biomaterial implants using label-free imaging.
13 Jun 2023,

Etich J, Semler O, Stevenson NL, Stephan A, Besio R, Garibaldi N, Reintjes N, Dafinger C, Liebau MC, Baumann U, Mörgelin M, Forlino A, Stephens DJ, Netzer C, Zaucke F, Rehberg M.
TAPT1-at the crossroads of extracellular matrix and signaling in Osteogenesis imperfecta.
9 Jun 2023,

Esho T, Kobbe B, Tufa SF, Keene DR, Paulsson M, Wagener R.
The Fraser Complex Proteins (Frem1, Frem2, and Fras1) Can Form Anchoring Cords in the Absence of AMACO at the Dermal-Epidermal Junction of Mouse Skin.
5 Apr 2023,

Becker L, Lu CE, Montes-Mojarro IA, Layland SL, Khalil S, Nsair A, Duffy GP, Fend F, Marzi J, Schenke-Layland K.
Raman microspectroscopy identifies fibrotic tissues in collagen-related disorders via deconvoluted collagen type I spectra.
16 Mar 2023,

Hassan N, Bückreiß N, Efing J, Schulz-Fincke M, König P, Greve B, Bendas G, Götte M.
The Heparan Sulfate Proteoglycan Syndecan-1 Triggers Breast Cancer Cell-Induced Coagulability by Induced Expression of Tissue Factor.
16 Mar 2023,

Kuhn A, Riegger J, Teixeira GQ, Huber-Lang M, Lambris JD, Neidlinger-Wilke C, Brenner RE.
Terminal Complement Activation Is Induced by Factors Released from Endplate Tissue of Disc Degeneration Patients and Stimulates Expression of Catabolic Enzymes in Annulus Fibrosus Cells.
13 Mar 2023,

Morgner J, Bornes L, Hahn K, López-Iglesias C, Kroese L, Pritchard CEJ, Vennin C, Peters PJ, Huijbers I, van Rheenen J.
A Lamb1Dendra2 mouse model identifies basement-membrane-producing origins and dynamics in PyMT breast tumors
6 Mar 2023,

Meier M, Gupta M, Akgül S, McDougall M, Imhof T, Nikodemus D, Reuten R, Moya-Torres A, To V, Ferens F, Heide F, Padilla-Meier GP, Kukura P, Huang W, Gerisch B, Mörgelin M, Poole K, Antebi A, Koch M, Stetefeld J.
The dynamic nature of netrin-1 and the structural basis for glycosaminoglycan fragment-induced filament formation.
3 Mar 2023,

Empere M, Wang X, Prein C, Aspberg A, Moser M, Oohashi T, Clausen-Schaumann H, Aszodi A, Alberton P.
Aggrecan governs intervertebral discs development by providing critical mechanical cues of the extracellular matrix.
2 Mar 2023,

Hassan N, Efing J, Kiesel L, Bendas G, Götte M.
The Tissue Factor Pathway in Cancer: Overview and Role of Heparan Sulfate Proteoglycans.
28 Feb 2023,

Manikowski D, Steffes G, Froese J, Exner S, Ehring K, Gude F, Di Iorio D, Wegner SV, Grobe K.
Drosophila hedgehog signaling range and robustness depend on direct and sustained heparan sulfate interactions.
22 Feb 2023,

Fan L, Ren Y, Emmert S, Vučković I, Stojanovic S, Najman S, Schnettler R, Barbeck M, Schenke-Layland K, Xiong X.
The Use of Collagen-Based Materials in Bone Tissue Engineering.
13 Feb 2023,

Gude F, Froese J, Manikowski D, Di Iorio D, Grad JN, Wegner S, Hoffmann D, Kennedy M, Richter RP, Steffes G, Grobe K.
Hedgehog is relayed through dynamic heparan sulfate interactions to shape its gradient.
10 Feb 2023,

Merline R, Rödig H, Zeng-Brouwers J, Poluzzi C, Tascher G, Michaelis J, Lopez-Mosqueda J, Rhiner A, Huber LS, Diehl V, Dikic I, Kögel D, Münch C, Wygrecka M, Schaefer L.
A20 binding and inhibitor of nuclear factor kappa B (NF-κB)-1 (ABIN-1): a novel modulator of mitochondrial autophagy.
1 Feb 2023,

Riegger J, Joos H, Möhler V, Leucht F, Rading K, Kubisch C, Ignatius A, Huber-Lang M, Brenner RE.
Functional Loss of Terminal Complement Complex Protects Rabbits from Injury-Induced Osteoarthritis on Structural and Cellular Level.
22 Jan 2023,

Espinoza-Sanchez NA, Troschel F, Greve B, Götte M.
Proteoglycan Expression Studied by MicroRNAs.
21 Jan 2023,

Zeng-Brouwers J, Huber LS, Merline R, Trebicka J, Wygrecka M, Schaefer L.
Evaluation of the In Vitro and In Vivo Effects of Biglycan in Innate Immunity.
21 Jan 2023,

Schäfer N, Grässel S.
New refinements aim to optimize articular cartilage tissue engineering.
5 Jan 2023,

Spanou CES, Wohl AP, Doherr S, Correns A, Sonntag N, Lütke S, Mörgelin M, Imhof T, Gebauer JM, Baumann U, Grobe K, Koch M, Sengle G.
Targeting of bone morphogenetic protein complexes to heparin/heparan sulfate glycosaminoglycans in bioactive conformation.
1 Jan 2023,


Urbanczyk M, Jeyagaran A, Zbinden A, Lu CE, Marzi J, Kuhlburger L, Nahnsen S, Layland SL, Duffy G, Schenke-Layland K.
Decorin improves human pancreatic β-cell function and regulates ECM expression in vitro.
30 Dec 2022,

Wank I, Niedermair T, Kronenberg D, Stange R, Brochhausen C, Hess A, Grässel S.
Influence of the Peripheral Nervous System on Murine Osteoporotic Fracture Healing and Fracture-Induced Hyperalgesia.
28 Dec 2022,

Schäfer N, Grässel S.
Targeted therapy for osteoarthritis: progress and pitfalls.
28 Dec 2022,

Rapp AE, Zaucke F.
Cartilage Extracellular Matrix-derived Matrikines in Osteoarthritis.
26 Dec 2022,

Willenborg S, Injarabian L, Eming SA.
Role of Macrophages in Wound Healing.
1 Dec 2022,

Merline R, Rödig H, Zeng-Brouwers J, Poluzzi C, Tascher G, Michaelis J, Lopez-Mosqueda J, Rhiner A, Huber LS, Diehl V, Dikic I, Kögel D, Münch C, Wygrecka M, Schaefer L.
A20 binding and inhibitor of nuclear factor kappa B (NF-κB)-1 (ABIN-1) - a novel modulator of mitochondrial autophagy.
28 Nov 2022,

Fromme JE, Dummer R, Mauch C, Zigrino P.
Tenascin C is a valuable marker for melanoma progression independent of mutational status and MAPK inhibitor therapy.
27 Nov 2022,

Stöckl S, Reichart J, Zborilova M, Johnstone B, Grässel S.
Semaphorin 3A-Neuropilin-1 Signaling Modulates MMP13 Expression in Human Osteoarthritic Chondrocytes.
16 Nov 2022,

Forte-Gomez HF, Gioia R, Tonelli F, Kobbe B, Koch P, Bloch W, Paulsson M, Zaucke F, Forlino A, Wagener R.
Structure, evolution and expression of zebrafish cartilage oligomeric matrix protein (COMP, TSP5). CRISPR-Cas mutants show a dominant phenotype in myosepta.
14 Nov 2022,

Buchert JM, Lotz B, Diederichs S, Richter W.
Adipose-Derived Stromal Cells: Isolation, Expansion, and Differentiation.
11 Nov 2022,

Adamo CS, Beyens A, Schiavinato A, Keene DR, Tufa SF, Mörgelin M, Brinckmann J, Sasaki T, Niehoff A, Dreiner M, Pottie L, Muiño-Mosquera L, Gulec EY, Gezdirici A, Braghetta P, Bonaldo P, Wagener R, Paulsson M, Bornaun H, De Rycke R, De Bruyne M, Baeke F, Devine WP, Gangaram B, Tam A, Balasubramanian M, Ellard S, Moore S, Symoens S, Shen J, Cole S, Schwarze U, Holmes KW, Hayflick SJ, Wiszniewski W, Nampoothiri S, Davis EC, Sakai LY, Sengle G, Callewaert B.
EMILIN1 deficiency causes arterial tortuosity with osteopenia and connects impaired elastogenesis with defective collagen fibrillogenesis.
8 Nov 2022,

Kümper M, Zamek J, Steinkamp J, Pach E, Mauch C, Zigrino P.
Role of MMP3 and fibroblast-MMP14 in skin homeostasis and repair.
23 Sep 2022,

Onyeisi JOS, Lopes CC, Götte M.
Role of syndecan-4 in breast cancer pathophysiology.
12 Sep 2022,

Przyklenk M, Heumüller SE, Freiburg C, Lütke S, Sengle G, Koch M, Paulsson M, Schiavinato A, Wagener R.
Lack of evidence for a role of anthrax toxin receptors as surface receptors for collagen VI and for its cleaved-off C5 domain/endotrophin.
12 Sep 2022,

Kümper M, Steinkamp J, Zigrino P.
Metalloproteinases in dermal homeostasis.
12 Sep 2022,

Riegger J, Maurer S, Pulasani S, Brenner RE.
Simvastatin and fluvastatin attenuate trauma-induced cell death and catabolism in human cartilage.
9 Sep 2022,

Willenborg S, Injarabian L, Eming SA.
Role of Macrophages in Wound Healing.
30 Aug 2022,

Zhang JL, Richetti S, Ramezani T, Welcker D, Lütke S, Pogoda HM, Hatzold J, Zaucke F, Keene DR, Bloch W, Sengle G, Hammerschmidt M.
Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2.
22 Aug 2022,

Zhang JL, Richetti S, Ramezani T, Welcker D, Lütke S, Pogoda HM, Hatzold J, Zaucke F, Keene DR, Bloch W, Sengle G, Hammerschmidt M.
Vertebrate extracellular matrix protein hemicentin-1 interacts physically and genetically with basement membrane protein nidogen-2.
22 Aug 2022,

Wang C, Stöckl S, Li S, Herrmann M, Lukas C, Reinders Y, Sickmann A, Grässel S.
Effects of Extracellular Vesicles from Osteogenic Differentiated Human BMSCs on Osteogenic and Adipogenic Differentiation Capacity of Naïve Human BMSCs.
11 Aug 2022,

Ivanova EL, Costa B, Eisemann T, Lohr S, Boskovic P, Eichwald V, Meckler J, Jugold M, Orian-Rousseau V, Peterziel H, Angel P.
CD44 expressed by myeloid cells promotes glioma invasion.
4 Aug 2022,

Marzi J, Munnig Schmidt EC, Brauchle EM, Wissing TB, Bauer H, Serrero A, Söntjens SHM, Bosman AW, Cox MAJ, Smits AIPM, Schenke-Layland K.
Marker-Independent Monitoring of in vitro and in vivo Degradation of Supramolecular Polymers Applied in Cardiovascular in situ Tissue Engineering.
17 May 2022,

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